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Publications in Scientific Journals and Book Chapters

Posted 01 March 2018 by In Publications

2019

 

View Articles published in Computational and Structural Biotechnology JournalA Web Tool for Ranking Candidate Drugs Against a Selected Disease Based on a Combination of Functional and Structural Criteria.
Karatzas E, Minadakis G, Kolios G, Delis A, Spyrou GM..
Comput Struct Biotechnol J. 2019 June 29;17:939-945.

 

Link to paper

 

 

Differential genetic and functional background in inflammatory bowel disease phenotypes of a Greek population: a systems bioinformatics approach.
Gazouli M, Dorvolis N, Franke A, Spyrou GM, Sechi LA, Kolios G.
Gut Pathog. 2019 June 15;11:31.

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46,XY complete gonadal dysgenesis in a fam ilial case with a rare mutation in the desert hedgehod (DHH) gene.
Neocleous V, Fanis P, Cinarli F, Kokotsis V, Oulas A, Toumba M, Spyrou GM, Phylactou LA, Skordis N.
Hormones (Athens). 2019 Jun 25. doi: 10.1007/s42000-019-00116-6. [Epub ahead of print]

 

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Issue CoverSystems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches.
   Oulas A   ,   Minadakis G  ,   Zacha riou M  ,  Sokratous K ,  Bour dakou MM , Spyrou GM .
Brief Bioinform. 2019 May 21;20(3):806-824

 

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Issue CoverComputational profiling of the gut-brain axis: microflora dysbiosis insights to neurological disorders.
Dovrolis N, Kolios G, Spyrou GM, Marouloukou I.
Brief Bioinform. 2019 May 21;20(3):825-841.

 

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Issue CoverPathwayConnector: finding complementary pathways to enhance functional analysis.
Minadakis G, Zachariou M, Oulas A, Spyrou GM.
Bioinformatics. 2019 March 1;35(5):889-891.

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Selecting variants of unknown significance through network-based gene-association significantly improves risk prediction for disease-control cohorts
Anastasis Oulas, George Minadakis, Margarita Zachariou, and George Spyrou 
Scientific Reports (Nature). 2019 Feb 1

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An Application of Computational Drug Repurposing Based on Transcriptomic Signatures.
Karatzas E, Kolios G, Spyrou GM.
Methods Mol Biol. 2019;1903:149-177.
 
 
 
 
Adjustment of vascular 2-deoxy-2[18F]fluoro-D-glucose uptake values over time through a modeling approach.
Kafouris PP, Koutagiar IP, goergakopoulos AT, Pianou NK, Metaxas MG, Spyrou GM, Anagnostopoulos CD.
Int J Cardiovasc Imaging. 2019 May;35(5):955-964.
 
 

Inhibition of breast cancer cell invasion by Ras suppressor-1 (RSU-1) silencing is reversed by Growth Differentiation Factor-15 (GDF-15)
Vasiliki Gkretsi, Maria Louca, Andreas Stylianou, George Minadakis, George Spyrou, Triantafyllos Stylianopoulos.
Int J Mol Sci. 2019 Jan 4;20(1)

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2018

 

Adjustment of vascular 2-deoxy-2-[18F]fluoro-D-glucose uptake values over time through a modeling approach
Pavlos Kafouris, Iosif Koutagiar, Alexandros Georgakopoulos, Nikoletta Pianou, Marinos Metaxas, George Spyrou, Constantinos Anagnostopoulos.  
The International Journal of Cardiovascular Imaging, December 2018

 

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Content driven clustering algorithm combining density and distance functions
Emmanouil K. Ikonomakis, George M Spyrou, Michael N Vrahatis
Pattern Recognition. Volume 87, March 2019, Pages 190-202
 

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PathwayConnector: finding complementary pathways to enhance functional analysis
George Minadakis, Margarita Zachariou, Anastasis Oulas, and George M. Spyrou
Bioinformatics . 2018 Aug 14. doi:10.1093/bioinformatics/bty693.
 

Link to the paper

 

 

Revealing Clusters of Connected Pathways through Multisource Data Integration in Huntington’s disease and Spastic Ataxia
Andrea C. Kakouri, Christiana C. Christodoulou, Margarita Zachariou, Anastasis Oulas, George Minadakis, Christiana A. Demetriou, Christina Votsi, Eleni-Zamba Papanicolaou, Kyproula Christodoulou, George M. Spyrou
IEEE Journal of Biomedical and Health Informatics . 2018 Aug

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Integrating multi-source information on a single network to detect disease-related clusters of molecular mechanisms.
 M. ZachariouG. MinadakisA. Oulas, S. Afxenti,  G. M. Spyrou
 J Proteomics. 2018 Mar 13. pii: S1874-3919(18)30104-0. doi: 10.1016/j.jprot.2018.03.009.

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Circulation: Cardiovascular Imaging, volume 11 issue 1 cover

18F-Fluorodeoxyglucose Positron Emission tomography/Computed Tomographic Imaging Detects Aortic Wall Inflammation in Patients With Repaired Coarctation of Aorta.
Brili S, Oikonomou E, antonopoulos AS. Pianou N, Georgakopoulos A, Koutagiar I, Kafouris P, Stroumpouli E, Dounis C, Metaxas M,  Spyrou G, Anagnostopoulos CD, and Tousoulis D.
Circ Cardiovasc Imaging. 2018 Jan 11(1):e007002. doi: 10.1161/CIRCIMAGING.117.007002.

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2017

 Systems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches.
 A. Oulas, G. Minadakis, M. Zachariou, K. Sokratous, M. M. Bourdakou, G. M. Spyrou.  
 Briefings in Bioinformatics. 2017 Nov 27. doi: 10.1093/bib/bbx151. 

 Link to the paper

 

 

 


 Computational profiling of the gut-brain axis: microflora dysbiosis insights to neurological disorders.

 Dovrolis N, Kolios G, Spyrou GM, Maroulakou I.  
 Briefings in Bioinformatics. 2017 Nov 27. doi: 10.1093/bib/bbx154.

 Link to the paper

 

 

 

 Informed walks: whispering hints to gene hunters inside networks' jungle. 
 Marilena M. Bourdakou and George M. Spyrou.
 BMC Systems Biology. 2017 Oct 11;11(1):97. doi: 10.1186/s12918-017-0473-6.

 Link to the paper

 

 

 

 Drug repurposing in idiopathic pulmonary fibrosis filtered by a bioinformatics-derived composite score.
 E. Karatzas, M. M. Bourdakou, G. Kolios & G. M. Spyrou
 Scientific Reports (Nature). 2017 Oct 3;7(1):12569. doi: 10.1038/s41598-017-12849-8.
  Link to the paper

 

 

 

 Laying in silico pipelines for drug repositioning: a paradigm in ensemble analysis for neurodegenerative diseases.
 Dovrolis Nikolas, Kolios George, Spyrou George, Maroulakou Ioanna.
 Drug Discov Today. 2017 Mar 29. pii: S1359-6446(17)30135-6.
Link to the paper

 

 

 

 Sediment microbial taxonomic and functional diversity in a natural salinity gradient challenge Remane’s "species minimum" concept.
 Christina Pavloudi, Jon B Kristoffersen, Anastasis Oulas, Marleen De Troch, Christos Arvanitidis.  
 PeerJ. 2017 Oct 13;5:e3687. doi: 10.7717/peerj.3687. eCollection 2017.
 Link to the paper

 

 

 Pharmacological Stimulation of Phagocytosis Enhances Amyloid Plaque Clearance; Evidence from a Transgenic Mouse Model of ATTR Neuropathy.
 Eleni Fella, Kleitos Sokratous, Revekka Papacharalambous, Kyriakos Kyriakou, Joy Phillips, Sam Sanderson, Elena Panayiotou, Theodoros Kyriakides.   
 Front. Mol. Neurosci. 2017 May 10;10:138. doi: 10.3389/fnmol.2017.00138. eCollection 2017.
 Link to the paper

 

 

 Fused man-machine classification schemes to enhance diagnosis of breast microcalcifications.
 Andreadis I, Chatzistergos S, Spyrou G, Nikita K.
 Meas. Sci. Technol. (2017) 28 114003
 Link to the paper

 

 

 

 

 Automatic cumulative sums contour detection of FBP-reconstructed multi-object nuclear medicine images.
 Protonotarios NE, Spyrou GM, Kastis GA.
 Comput Biol Med. 2017 Jun 1;85:43-52. doi: 10.1016/j.compbiomed.2017.04.010. Epub 2017 Apr 14.

 Link to the paper

 

 

 

2016

 Seqenv: linking sequences to environments through text mining.
 L Sinclair, U Z Ijaz, L J Jensen, M Coolen, C Gubry-Rangin, S Berger, A Chroňáková, A Oulas, C Pavloudi, J Schnetzer, A Weimann, A Z Ijaz, A Eiler, C Quince, E Pafilis.  
 PeerJ. 2016 Dec 20;4:e2690. doi: 10.7717/peerj.2690. eCollection 2016.
 Link to the paper